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Among the 4 patients who developed thyroid dysfunction in the Abs-negative group, two had a positive anti-thyroid antibody status at thyroid dysfunction onset (positive TgAb and TPOAb in one and positive TgAb in the other patient), suggesting the involvement of thyroid autoimmunity even in patients negative for anti-thyroid antibodies at baseline

Given the frequent occurrence of anxiety, depression, and other psychiatric conditions in individuals with ME/CFS, exploring alternatives to traditional psychotropic drugs is essential [88]

In summary, there is already substantial evidence that ferroptosis plays a vital role in myocardial injury caused by MIR and various types of cardiomyopathy

On the other hand, GLP-1 RA can reduce epicardial fat and semaglutide 2.4 mg have shown to improve physical function and symptoms in people with HFpEF [93]

RDA and an upper suggestion to meet the European Food Safety Authoritys adequate intake